Abstract
Çeşitli psikiyatrik bozuklukların tedavisinde kullanılan ketiapin deri döküntüsüne neden olabilir. Bu olgu sunumunda, ketiapin kullanımı ile ilişkili deri döküntüsünü sunduk. Yaygın anksiyete bozukluğu tanısıyla takip edilen ve uykusuzluk şikâyetine yönelik olarak ketiapin 200 mg/gün başlanan 43 yaşındaki erkek hastada tedavinin yedinci gününde yüz, saçlı deri ve boyun bölgesiyle sınırlı deri döküntüsü ortaya çıktı. İlaç başlanmasınu takiben ortaya çıkan bu yan etki ketiapin kullanımı ile ilişkilendirildi ve ilaç kesildi. Ketiapin kesilmesini takiben deri döküntüsü giderek azaldı ve üç haftanın sonunda tamamen ortadan kayboldu. Hastanın yaygın anksiyete bozukluğu ile ilişkili tedavisi tamamlandı ve taburcu edildi. Takiplerinde deri döküntüsü gözlenmedi. Deri ile ilişkili yan etkiler ketiapin kullanımı ile ilişkili olabilir. Klinisyenler, ketiapinin deri döküntüsü yan etkisine karşı uyanık olmalıdır.
Keywords
References
- Rowe, D.L. (2007). Off-label prescription of quetiapine in psychiatric disorders. Expert Review of Neurotherapeutics 7(7), 841-852.
- Joshi, M., Kumar, S. (2023). Allergic cutaneous drug eruptions with quetiapine: a case study. Indian Journal of Psychological Medicine, 45(4), 441-442.
- Kose, S., Akin, E., Cetin, M. (2017). Adverse drug reactions and causality: The Turkish version of naranjo adverse drug reactions probability scale. Psychiatry and Clinical Psychopharmacology, 27(2), 205-206.
- Edwards, I.R., Biriell, C. (1994). Harmonisation in pharmacovigilance. Drug Safety, 10, 93-102.
- Biju, R.A., Davis, S., Sanal, G. (2022). Quetiapine‑induced drug rash with eosinophilia and systemic symptom syndrome. Journal of Medical Sciences, 42(5), 242‑244.
- Lasić, D., Ivanišević, R., Uglešić, B., Cvitanović, M.Z., Glučina, D., Hlevnjak, I. (2013). Acute generalized exanthematous pustulosis as a side effect of quetiapine. Psychiatria Danubina, 25(1), 84-85.
- Ram, D., Mathur, S. (2019). Quetiapine-induced leukocytoclastic vasculitis. Indian Journal of Pharmacology, 51(4), 282-283.
- Lin, G.L., Chiu, C.H., Lin, S.K. (2006). Quetiapine-induced erythema multiforme minor: a case report. Journal of Clinical Psychopharmacology, 26(6), 668-669.
Abstract
Quetiapine, used in the treatment of various psychiatric disorders, can cause skin rash. In this case report, we presented a skin rash associated with quetiapine use. A 43-year-old male patient, who was followed up with the diagnosis of generalized anxiety disorder and was started on quetiapine 200 mg/day for insomnia, developed a skin rash limited to the face, scalp, and neck area on the seventh day of treatment. This side effect that occurred after the drug was started was associated with the use of quetiapine and the drug was discontinued. After discontinuation of quetiapine, the skin rash gradually decreased and disappeared completely after three weeks. The patient's treatment for generalized anxiety disorder was completed and he was discharged. No skin rash was observed in the follow-ups. Skin-related side effects may be associated with quetiapine use. Clinicians should be alert to the rash side effect of quetiapine.
Keywords
References
- Rowe, D.L. (2007). Off-label prescription of quetiapine in psychiatric disorders. Expert Review of Neurotherapeutics 7(7), 841-852.
- Joshi, M., Kumar, S. (2023). Allergic cutaneous drug eruptions with quetiapine: a case study. Indian Journal of Psychological Medicine, 45(4), 441-442.
- Kose, S., Akin, E., Cetin, M. (2017). Adverse drug reactions and causality: The Turkish version of naranjo adverse drug reactions probability scale. Psychiatry and Clinical Psychopharmacology, 27(2), 205-206.
- Edwards, I.R., Biriell, C. (1994). Harmonisation in pharmacovigilance. Drug Safety, 10, 93-102.
- Biju, R.A., Davis, S., Sanal, G. (2022). Quetiapine‑induced drug rash with eosinophilia and systemic symptom syndrome. Journal of Medical Sciences, 42(5), 242‑244.
- Lasić, D., Ivanišević, R., Uglešić, B., Cvitanović, M.Z., Glučina, D., Hlevnjak, I. (2013). Acute generalized exanthematous pustulosis as a side effect of quetiapine. Psychiatria Danubina, 25(1), 84-85.
- Ram, D., Mathur, S. (2019). Quetiapine-induced leukocytoclastic vasculitis. Indian Journal of Pharmacology, 51(4), 282-283.
- Lin, G.L., Chiu, C.H., Lin, S.K. (2006). Quetiapine-induced erythema multiforme minor: a case report. Journal of Clinical Psychopharmacology, 26(6), 668-669.
Details
| Primary Language | Turkish |
|---|---|
| Subjects | Psychiatry |
| Journal Section | Olgu Sunumu |
| Authors | |
| Publication Date | November 30, 2023 |
| Published in Issue | Year 2023 Volume: 2 Issue: 3 |
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